Disseminated Intravascular Coagulation

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Disseminated Intravascular Coagulation

Post  David on Wed Jun 10, 2009 8:25 am

From Janine and Baron
This is a rare, life-threatening condition that prevents a wombats blood from clotting normally. In DIC the body's natural ability to regulate blood clotting does not function properly. This causes the blood's clotting cells (platelets) to clump together and clog small blood vessels throughout the body. This excessive clotting damages organs, destroys blood cells and depletes the supply of platelets and other clotting factors so that the blood is no longer able to clot normally.
It is caused by severe trauma (which Sally had on arrival 7 weeks earlier), some types of snakebite, burns, some cancers or the mother ingesting rat poison (who knows?).
It is also known as consumptive coagulopathy - a pathological process in the body where the blood starts to coagulate throughout the whole body. This depletes the body of its platelets and coagulation factors, resulting in the paradoxic situation in which there is a high risk for simultaneous catastrophic thrombosis as well as massive haemorrhage.
DIC is a very complex condition that can be hard to diagnose. A full blood count is important(especially the platelet count), bleeding time and fibrinogen levels. In Sally's case by the time she showed symptoms it was too late. Prior to her "bleed" the only abnormality was her weight was a little behind in gaining what she should but not drastic.
The prognosis for those with DIC, regardless of cause, is grim, leading the initials to be known colloquially as "death is coming"

From Howard Ralph
Disseminated Intravascular Coagulopathy) is certainly a nasty condition. It is also rare in most species and often follows an unknown cause which triggers the aberrant coagulation process. One would have to be able to measure fibrinogen and in particular 'fibrin degredation products'. These tests are not always readily available. Treatment is also difficult running a compromise course between clotting and bleeding. Even with human primates in the most high tech ICU the results of treatment are not encouraging. Poor little bloke.
Regards
Howard
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